Transtubular Potassium Gradient Calculation

Transtubular potassium gradient (TTKG) is an index reflecting the conservation of potassium in the cortical collecting ducts of the kidneys. It is useful in diagnosing the cause of hyperkalemia.

Transtubular Potassium Gradient (TTKG) Calculator

Urine K (mmol/L)
TPlasma osmolality (mmol/kg)
Plasma K (mmol/L)
Urine osmolality (mmol/kg)
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TTKG = (Urine K * Plasmaosm) / (Plasma K *Urineosm) Where, TTKG = Transtubular Potassium Gradient Urine K = Urine potassium (in mEq/L or mmol/L) Plasma K = Plasma potassium (in mEq/L or mmol/L) Plasmaosm = Plasma osmolality (in mOsm/kg or mmol/kg) Urineosm = Urine osmolality (in mOsm/kg or mmol/kg)

During potassium depletion or hypokalemia, the TTKG should fall to less than 3, indicating appropriately reduced urinary excretion of potassium. Free online Medical Calculators.

Note :This statistics calculator is presented for your own personal use and is to be used as a guide only. Medical and other decisions should NOT be based on the results of this calculator. Although this calculator has been tested, we cannot guarantee the accuracy of its calculations or results.

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