Formula:

Metabolic Acidosis Compensation: Winters Formula
PaCO2 = [(1.5*HCO3) + 8] ± 2
where,
PaCO2=arterial part press CO2
Assesses adequacy of compensation for metabolic acidosis
If calculated PaCO2 = actual PaCO2, then compensation adequate.
If actual > calculated, then both met and resp acidosis present.
If actual < calculated, then met acidosis & resp alkalosis present.

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